2 January 2025
Guided Ketogenic diet ? – what is it, how does it work? Humans are evolutionary adapted to use any of the macro nutrients (fats, proteins, carbohydrates) for energy. Ketosis is a metabolic state in which your body uses stored fat rather than carbohydrates as your main energy source. Ketogenic diets are being used not only for weight loss but also as a tool for metabolic healing. This is because ketosis · Takes the reliance off the adrenals for blood sugar regulation ( therefore benefits those with blood sugar/ insulin resistance problems) 1 · Resets leptin, the hormone that controls appetite and also energy expenditure, so helps to regulate energy balance, which is important to support healing · Aids weight loss. Ketogenic diets can yield greater weight loss over medium carbohydrate diets 2, 3 and low fat, medium carb diets 4,5 . This is because eating excess refined carbohydrates leads to fat storage. High natural healthy fat intake leads to fat loss · Promotes fat cycling, rather than storage, can also encourage elimination of any fat soluble toxins stored in your fat cells 6 · Originally designed to offset excitatory brain agitation in epilepsy, ketosis calms the neural activity and is also being used for Alzheimers, Parkinson, migraines and other neural degenerative diseases 7 · Ketones are anti inflammatory so drive down any other inflammation to allow healing and this is being investigated for reducing cancer tumours 7,8,9 However! , there are however pitfalls and this needs to be entered with caution and guidelines so you don’t do yourself more harm than good. This includes - Getting the right balance of nutrients with a high fat, moderate protein and low carbohydrates - Guidance for transition into ketosis as unguided this can be stressful on the body - Making sure you are not in ketosis long term as this can down regulate your metabolism - Consideration of adaptations of the ketogenic diet for those undertaking cardio/ aerobic/ athletic training I had a step change in my own health when following a guided ketogenic diet. If you are interested in trying a guided ketogenic diet to help your health then please feel free to get in touch . 1. Effect of a low-carbohydrate diet on appetite, blood glucose levels, and insulin resistance in obese patients with type 2 diabetes. Boden G , Sargrad K , Homko C , Mozzoli M , Stein TP . Ann Intern Med. 2005 Mar 15;142(6):403-11. 2. Effects of a high-protein ketogenic diet on hunger, appetite, and weight loss in obese men feeding ad libitum. Johnstone AM , Horgan GW , Murison SD , Bremner DM , Lobley GE . Am J Clin Nutr. 2008 Jan;87(1):44-55. 3. Body composition and hormonal responses to a carbohydrate-restricted diet. Volek JS , Sharman MJ , Love DM , Avery NG , Gómez AL , Scheett TP , Kraemer WJ . Metabolism. 2002 Jul;51(7):864-70. 4. Twelve-month outcomes of a randomized trial of a moderate-carbohydrate versus very low-carbohydrate diet in overweight adults with type 2 diabetes mellitus or prediabetes. Saslow LR , Daubenmier JJ , Moskowitz JT , Kim S , Murphy EJ , Phinney SD , Ploutz-Snyder R , Goldman V , Cox RM , Mason AE , Moran P , Hecht FM . Nutr Diabetes. 2017 Dec 21;7(12):304. 5. A randomized trial comparing a very low carbohydrate diet and a calorie-restricted low fat diet on body weight and cardiovascular risk factors in healthy women. Brehm BJ , Seeley RJ , Daniels SR , D'Alessio DA . J Clin Endocrinol Metab. 2003 Apr;88(4):1617-23. 6. Fats that heal and Fats that Kill , Udo Erasmus, Alive books, 1993 7. Potential for diet to prevent and remediate cognitive deficits in neurological disorders. Francis HM , Stevenson RJ . Nutr Rev. 2018 Jan 15. doi: 10.1093/nutrit/nux073. [Epub ahead of print] 8. Obesity and tumor growth: inflammation, immunity, and the role of a ketogenic diet. Wright C 1 , Simone NL . Current Opinion in Clinical Nutrition & Metabolic Care: July 2016 - Volume 19 - Issue 4 - p 294–299 9. The calorically restricted ketogenic diet, an effective alternative therapy for malignant brain cancer. Zhou W , Mukherjee P , Kiebish MA , Markis WT , Mantis JG , Seyfried TN . Nutr Metab (Lond). 2007 Feb 21;4:5.